| Effect of menopausal status on long-term outcome of women undergoing drug-eluting stent implantation |
| Received:August 14, 2020 Revised:October 07, 2020 Click here to download the full text |
| Citation of this paper:WANG Xiang-fei,DORJE Ta-shi,WANG Qi-bing,FAN Bing,QIAN Ju-ying,GE Lei,MA Jian-ying,ZHANG Feng,YAO Kang,GE Jun-bo.Effect of menopausal status on long-term outcome of women undergoing drug-eluting stent implantation[J].Chinese Journal of Clinical Medicine,2021,28(2):258-261 |
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| Author Name | Affiliation | E-mail | | WANG Xiang-fei | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | DORJE Ta-shi | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | WANG Qi-bing | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | FAN Bing | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | QIAN Ju-ying | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | GE Lei | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | MA Jian-ying | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | ZHANG Feng | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | YAO Kang | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | GE Jun-bo | Department of Cardicology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | ge.junbo@zs-hospital.sh.cn |
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| Abstract:Objective: To explore the relationship between menopausal status and long-term outcome of patients with coronary heart disease (CHD) after drug-eluting stent implantation. Methods: The data of 143 patients with CHD who were less than 55 years old and implanted with drug-eluting stents in Zhongshan Hospital, Fudan University from January 2008 to December 2014 were retrospectively analyzed. According to the status of menopause, patients were divided into premenopausal women group (n=50) and postmenopausal women group (n=93). Results: Compared with the postmenopausal women, the premenopausal women were younger, and had a higher rate of positive family history of CHD. The median follow-up time was 823 days. The incidence of major cardiac adverse events (MACEs) was not significantly different between the two groups. The event-free survival rate was not significantly different between the two groups. Cox regression analysis showed that the independent predictors of MACEs included the multi-vessel disease and lower estimated GFR other than menopausal status. Conclusions: In women with CHD, the premenopausal status might not be a influence factor for MACEs. |
| keywords:coronary artery disease percutaneous coronary intervention drug-eluting stent female menopause |
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