| Early predictive value of contrast-enhanced ultrasonography for delayed graft function in renal transplantation patients |
| Received:July 24, 2020 Revised:November 25, 2020 Click here to download the full text |
| Citation of this paper:SONG Jie-qiong,ZHANG Jin-cheng,LIN Shi-long,LENG Fei,RONG Rui-ming,XU Ming,ZHONG Ming.Early predictive value of contrast-enhanced ultrasonography for delayed graft function in renal transplantation patients[J].Chinese Journal of Clinical Medicine,2021,28(2):278-282 |
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| Author Name | Affiliation | E-mail | | SONG Jie-qiong | Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | ZHANG Jin-cheng | Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | LIN Shi-long | Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | LENG Fei | Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | RONG Rui-ming | Department of Urology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | XU Ming | Department of Urology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | ZHONG Ming | Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | zhong.ming@zs-hospital.sh.cn |
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| Abstract:Objective: To explore the early predictive value of contrast-enhanced ultrasonography (CEUS) for delayed graft function (DGF) in renal transplantation patients. Methods: From April 2017 to March 2018, 68 patients with renal allograft who underwent routine ultrasound and CEUS examination on the first day after operation at the Department of Urology, Zhongshan Hospital, Fudan University were included. The patients were divided into normal graft function group (NGF group, n=58) and delayed graft function group (DGF group, n=10). Transplanted kidney size, peak systolic velocity (PSV) and resistance index (RI) of segmental and interlobar arteries were recorded. The time-intensity curve (TIC) of transplant renal cortex was performed through CEUS, and the rise time (RT), rising slope (k), peak intensity (PI), time to peak (TTP), mean transit time (mTT), and the area under the curve (AUC) were recorded. Results: Doppler ultrasound showed that the RI values of segmental artery and interlobar artery in the DGF group were significantly higher than those in the NGF group (P<0.01). CEUS showed that the PI and the AUC in the DGF group were significantly lower than those in the NGF group (P<0.05). The other ultrasound parameters showed no statistically significant differences between the two groups. Conclusions: CEUS can quantitatively analyze the microcirculation of transplant kidney, and has the advantages of non-invasiveness and high repeatability which are of great clinical value for the early diagnosis of DGF. |
| keywords:renal transplantation delayed graft function contrast-enhanced ultrasonography contrast media |
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