| Application value of magnetic resonance diffusion kurtosis imaging in predicting TN stage, differentiation and vascular invasion of rectal cancer |
| Received:August 18, 2020 Revised:October 28, 2020 Click here to download the full text |
| Citation of this paper:DUAN Shu-feng,YU Xiao-lu,FENG Feng.Application value of magnetic resonance diffusion kurtosis imaging in predicting TN stage, differentiation and vascular invasion of rectal cancer[J].Chinese Journal of Clinical Medicine,2020,27(6):1020-1025 |
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| Author Name | Affiliation | E-mail | | DUAN Shu-feng | Department of Imaging, Nantong Tumor Hospital, Nantong 226001, Jiangsu, China | | | YU Xiao-lu | School of Nursing, Naval Medical University, Shanghai 200433, China | yuxiaolu0509@163.com | | FENG Feng | Department of Imaging, Nantong Tumor Hospital, Nantong 226001, Jiangsu, China | drfengfeng@163.com |
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| Abstract:Objective:To explore the value of magnetic resonance diffusion kurtosis imaging (DKI) in the prediction of TN staging, differentiation and vascular invasion of rectal cancer.Methods:Forty-three patients with rectal cancer hospitalized in our hospital from 2017 to 2019 underwent routine MRI and DKI were selected, and DKI parameters were obtained by post-processing software. The lesions were resected and sent for pathological examination within one week.Results:With the increase of T staging, the MK value increased, and the difference of each parameter in each group of patients was statistically significant (P<0.05), and the MD value was not significantly different. The lower the degree of pathological differentiation of rectal adenocarcinoma, the lower the MD value, and the higher the MK value. The overall differences in each group of patients were statistically significant (P<0.05). The MK value of cases with vascular invasion was greater than that without vascular invasion, and the difference between the two was statistically significant (P<0.05), with an AUC of 0.772, a sensitivity of 81.0%, and a specificity of 68.7%; there was no statistical difference in MD values. MK and MD values are statistically significant between the two groups of rectal cancer with lymph node metastasis (P<0.05).Conclusions:MK value can assist in the diagnosis of rectal cancer T staging. MK and MD values can predict the degree of pathological differentiation of rectal cancer. The MK value can be used to predict whether there is vascular invasion around rectal cancer. MK and MD can assist in the diagnosis of lymph node metastasis in rectal cancer, and the combination of MK and MD has better diagnostic efficiency. |
| keywords:MRI DKI rectal cancer TN stage pathological grading vascular invasion |
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