| Stereotactic body radiotherapy with 50 Gy in 10 fractions for unresectable liver metastasis |
| Received:February 12, 2020 Revised:September 10, 2020 Click here to download the full text |
| Citation of this paper:LU Zhen-guo,SUN Jun-die,XIANG Zuo-lin,LU Xin,WANG Ai-hua,YUAN Jun.Stereotactic body radiotherapy with 50 Gy in 10 fractions for unresectable liver metastasis[J].Chinese Journal of Clinical Medicine,2020,27(6):1007-1010 |
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| Author Name | Affiliation | E-mail | | LU Zhen-guo | Department of Radiation Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China | | | SUN Jun-die | Department of Radiation Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China | | | XIANG Zuo-lin | Department of Radiation Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China | xiangzuolinmd@hotmail.com | | LU Xin | Department of Radiation Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China | | | WANG Ai-hua | Department of Radiation Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China | | | YUAN Jun | Department of Radiation Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China | |
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| Abstract:Objective:To explore the clinical efficacy of stereotactic body radiotherapy (SBRT) for the treatment of patients with unresectable liver metastasis. Methods:Data of 28 patients with unresectable liver metastases were retrospectively analyzed. All patients were admitted to the Shanghai East Hospital from March 2018 to November 2019. Patients underwent 4D-CT or respiration gating for CT simulation. The prescription dose for the liver metastasis was 50 Gy in 10 fractions. Results:All patients successfully completed the SBRT treatment. The median overall survival was 7.4 months. The six months and one-year survival rates were 95.0% and 70.1%, respectively. The local control rate for one year was 92.2%. The most common toxicity was grade Ⅰ or Ⅱ nausea, poor appetite, and abdominal pain. No grade Ⅲ or worse toxicity was found. Conclusions:SBRT with 50 Gy in 10 fractions is a safe and effective treatment for patients with unresectable liver metastasis. |
| keywords:liver metastasis stereotactic body radiotherapy (SBRT) colorectal cancer |
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