| Clinical study on the treatment of trigeminal neuralgia and post-herpetic neuralgia with botulinum toxin type A |
| Received:April 01, 2020 Revised:May 07, 2020 Click here to download the full text |
| Citation of this paper:LI Hua-liang,PAN Ping-lei,CHEN Jia-hui,LUO Rong,SHEN Yuan,ZHONG Jian-guo.Clinical study on the treatment of trigeminal neuralgia and post-herpetic neuralgia with botulinum toxin type A[J].Chinese Journal of Clinical Medicine,2020,27(5):834-836 |
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| Author Name | Affiliation | E-mail | | LI Hua-liang | Department of Neurology, the Third People's Hospital of Yancheng, Yancheng 224005, Jiangsu, China | | | PAN Ping-lei | Department of Neurology, the Third People's Hospital of Yancheng, Yancheng 224005, Jiangsu, China | | | CHEN Jia-hui | Department of Neurology, the Third People's Hospital of Yancheng, Yancheng 224005, Jiangsu, China | | | LUO Rong | Department of Neurology, the Third People's Hospital of Yancheng, Yancheng 224005, Jiangsu, China | | | SHEN Yuan | Department of Neurology, the Third People's Hospital of Yancheng, Yancheng 224005, Jiangsu, China | | | ZHONG Jian-guo | Department of Neurology, the Third People's Hospital of Yancheng, Yancheng 224005, Jiangsu, China | jsyczjg@126.com |
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| Abstract:Objective: To observe the clinical effect of botulinum toxin type A (BTX-A) on trigeminal neuralgia (TN) and post-herpetic neuralgia (PHN). Methods: Thirty-three patients with TN or PHN were treated by subcutaneous or intradermal injection of BTX-A into the pain area, the patients' numerical rating scale (NRS), sleep status and quality of life (QOL) at the time of treatment, 2 weeks after treatment, and 3 months after treatment were evaluated, the treatment effect and the drug adverse reactions were analyzed. Results: After 2 weeks and 3 months of treatment with BTX- A, NRS and sleep score of the patients were significantly lower than those at the time of treatment (P<0.05), QOL was significantly higher than that at the time of treatment (P<0.05). Treatment effect was good and few side effects were observed. Conclusions: BTX-A is effective in treating TN and PHN and can become a new therapeutic approach for neuropathic pain. |
| keywords:botulinum toxin-A trigeminal neuralgia post-herpetic neuralgia |
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