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Diagnosis and treatment of thoraco-omphalopagus conjoined twins with complex cardiac malformation in a fetus
Received:April 27, 2020  Revised:June 16, 2020  Click here to download the full text
Citation of this paper:FENG Zhong,LI Jun,SONG Zai,DONG Chen-bin,DONG Kui-ran,JIA Bing,WANG Xuan,SHEN Jie,SHEN Chun.Diagnosis and treatment of thoraco-omphalopagus conjoined twins with complex cardiac malformation in a fetus[J].Chinese Journal of Clinical Medicine,2020,27(5):785-790
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Author NameAffiliationE-mail
FENG Zhong Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China  
LI Jun Department of Plastic Surgery, Children's Hospital of Fudan University, Shanghai 201102, China  
SONG Zai Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China  
DONG Chen-bin Department of Plastic Surgery, Children's Hospital of Fudan University, Shanghai 201102, China  
DONG Kui-ran Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China  
JIA Bing Cardiac Center, Children's Hospital of Fudan University, Shanghai 201102, China  
WANG Xuan Department of Anesthesiology, Children's Hospital of Fudan University, Shanghai 201102, China  
SHEN Jie Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China  
SHEN Chun Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai 201102, China chunshen@fudan.edu.cn 
Abstract:Objective: To introduce the experience of the special treatment of the thoraco-omphalopagus conjoined twins, one of which has complex heart malformation. Methods: A case of thoraco-omphalopagus conjoined twins, one was accompanied by congenital heart malformation, the twins who received the prenatal diagnosis and were born in the Obstetrics and Gynecology Hospital of Fudan University and received treatment in the Children's Hospital of Fudan University were selected. The related diagnosis, treatment, and specific clinical manifestation were summarized to provide individualized therapy. Results: After the full-term cesarean section, two children were largely different in urine volume and gained weight relatively slowly. In addition, the child with heart malformation was observed cyanosis after noisy crying when she was 1-month old. The conjoined twins underwent separation on the 38th day after birth. Nine days after the separation, the child with heart malformation underwent Blalock-Taussig (BT) shunt. Two weeks after the separation, the child without heart disease was successfully discharged from the hospital. Twenty days after B-T shunts, the child complicated with congenital heart disease was also discharged successfully. Conclusions: Although thoraco-omphalopagus is the most frequent type of conjoined twins, the risk of surgery increases when it is complicated with cardiac malformation. An individualized treatment plan should be formulated in consideration of the degree of heart disease and clinical manifestations, thus improving the success rate of treatment.
keywords:conjoined twins  cardiac malformation  comorbidity  separation
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