| Prevention and control of nosocomial infection of cutaneous anthrax under the guidance of metagenomic next-generation sequencing: a case report |
| Received:August 06, 2020 Revised:August 21, 2020 Click here to download the full text |
| Citation of this paper:CHEN Xiang,GAO Xiao-dong,HU Bi-jie,SHI Lei,LIN Jia-bing.Prevention and control of nosocomial infection of cutaneous anthrax under the guidance of metagenomic next-generation sequencing: a case report[J].Chinese Journal of Clinical Medicine,2020,27(4):575-577 |
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| Author Name | Affiliation | E-mail | | CHEN Xiang | Department of Hospital Infection Management, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | GAO Xiao-dong | Department of Hospital Infection Management, Zhongshan Hospital, Fudan University, Shanghai 200032, China | gaoxd5@vip.sina.com | | HU Bi-jie | Department of Hospital Infection Management, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Infectious Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China | hubijie@vip.sina.com | | SHI Lei | Department of Infection Control, Shanghai Pubilc Health Clinical Center, Fudan University, Shanghai 200032, China | | | LIN Jia-bing | Department of Hospital Infection Management, Zhongshan Hospital, Fudan University, Shanghai 200032, China | |
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| Abstract:Anthrax is a zoonosis caused by Bacillus anthracis, which is mainly skin anthrax and belongs to the legal class B infectious disease in China. A 33-year-old male patient presented with a rash on his right forearm after insect bite. After the rash is broken by himself, it appears redness and blisters with a small amount of pus. The result of conventional microbial culture was negative, while the metagenomic next-generation sequencing (mNGS) of blood sample revealed Bacillus anthracis. This study discusses the clinical application value of mNGS from the perspective of early diagnosis of cutaneous anthrax and the prevention and control of nosocomial infection. |
| keywords:anthraxm metagenomic next-generation sequencing hospital infection control |
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