| Clinical characteristics analysis of severe novel coronavirus pneumonia cases |
| Received:February 25, 2020 Revised:February 28, 2020 Click here to download the full text |
| Citation of this paper:PENG Ping,CHEN Mu,XU Li-xian,PENG Hui,MO Xiao-neng.Clinical characteristics analysis of severe novel coronavirus pneumonia cases[J].Chinese Journal of Clinical Medicine,2020,27(2):202-205 |
| Hits: 3230 |
| Download times: 1456 |
| Author Name | Affiliation | E-mail | | PENG Ping | Department of Respiratory Medicine, Guangzhou Eighth People's Hospital affiliated to Guangzhou Medical University, Guangzhou 510060, Guangdong, China | | | CHEN Mu | Department of Respiratory Medicine, Guangzhou Eighth People's Hospital affiliated to Guangzhou Medical University, Guangzhou 510060, Guangdong, China | | | XU Li-xian | Department of Respiratory Medicine, Guangzhou Eighth People's Hospital affiliated to Guangzhou Medical University, Guangzhou 510060, Guangdong, China | | | PENG Hui | Department of Respiratory Medicine, Guangzhou Eighth People's Hospital affiliated to Guangzhou Medical University, Guangzhou 510060, Guangdong, China | | | MO Xiao-neng | Department of Respiratory Medicine, Guangzhou Eighth People's Hospital affiliated to Guangzhou Medical University, Guangzhou 510060, Guangdong, China | moxiaoneng@126.com |
|
| Abstract:Objective: To guide clinical diagnosis prediction and treatment by analyzing the clinical characteristics of 12 patients with severe novel coronavirus pneumonia (COVID-19) retrospectively. Methods: 12 patients with severe COVID-19, who were treated in the third isolation area of Guangzhou Eighth People's Hospital from Janunary to February 2020 were selected. Dynamic changes of clinical symptoms, routine blood test of lymphocyte count, oxygenation index, liver and kidney function, and chest CT were observed to analyze its clinical characteristics. Results: 11 severe COVID-19 patients had fever, 12 cases coughed, 9 cases with dyspnea, 11 cases with fatigue, and 11 cases of anorexia. The absolute value of lymphocytes in severe COVID-19 patients decreased significantly. The lowest value was (0.66±0.23)×109/L, which lasted for (12.09±5.91) days. The oxygenation index decreased significantly, its lowest value was (166.08±59.05) mmHg(1 mmHg=0.133 kPa), and the oxygenation index below 300 mmHg lasted for (10.00±4.95) days. Early chest CT showed multi-lobed with multiple patches or ground glass in both lungs. The range of the image increased as the disease progressed, the lungs were partially consolidated, a few with pleural effusion. Chest CT image showed that 66.67% patients in the recovery period with fiber strands image. Conclusions: Blood routine lymphocyte value, oxygenation index value, and early chest CT characteristics represent the important indicators for the patients with severe COVID-19, and are of great significance in early treatment for severe COVID-19 patients. |
| keywords:lymphocyte oxygenation index COVID-19 |
| HTML View Full Text View/Add Comment Download reader |
|
|
|