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Characteristics of left atrial appendage in patients with non-valvular atrial fibrillation
Received:April 28, 2020  Revised:May 21, 2020  Click here to download the full text
Citation of this paper:LIU Gui-jian,LI Ya-na,CHEN Rui-zhen,ZHU Wen-qing,GE Jun-bo.Characteristics of left atrial appendage in patients with non-valvular atrial fibrillation[J].Chinese Journal of Clinical Medicine,2020,27(3):453-456
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Author NameAffiliationE-mail
LIU Gui-jian Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China 
 
LI Ya-na Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China  
CHEN Rui-zhen Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China 
 
ZHU Wen-qing Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China 
zhu.wenqing@zs-hospital.sh.cn 
GE Jun-bo Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China 
 
Abstract:Objective: To explore the characteristics of left atrial appendage (LAA) in patients with non-valvular atrial fibrillation (AF).Methods: From January 1, 2019 to December 31, 2019, 237 patients of AF were collected from Zhongshan Hospital, Fudan University. The differences of internal diameter and length of LAA orifice and LAA ejection rate between paroxysmal AF(n=106) and persistent AF(n=131) were analyzed retrospectively. The clinical related factors of internal diameter, length and ejection rate of LAA orifice in patients with AF were analyzed.Results: Diameter of LAA orifice was significantly larger in persistent AF group than paroxysmal AF group (P<0.05). There was no significant difference in LAA length and LAA ejection rate between the two groups. Spearman correlation coefficient analysis showed that diameter of LAA orifice was positively correlated with body height, duration of AF, left atrial diameter, left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD),and was negatively correlated with left ventricular ejection fraction (LVEF), (P<0.05). Length of LAA was positively correlated with left atrial diameter, LVESD, LVEDD and was negatively correlated with LVEF (P<0.05);LAA ejection velocity was negatively correlated with age,duration of AF,left atrial diameter,LVESD,and positively correlated with LVEF (P<0.05).Conclusions: Compared with paroxysmal AF patients,persistent AF patients had larger LAA ostium. The diameter of LAA orifice, LAA length and ejection velocity are correlated with height, history of AF, left atrium diameter and so on.
keywords:non-valvular atrial fibrillation  paroxysmal atrial fibrillation  persistent atrial fibrillation  left atrial appendage
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