| The analysis of re-positive rate of throat swab nucleic acid test in ordinary patients with COVID-19 |
| Received:March 15, 2020 Revised:April 29, 2020 Click here to download the full text |
| Citation of this paper:LIANG Chao,FEI Min,LING Xiao-min,GE Feng,LUO Jian-fei,CANG Jing,MIAO Chang-hong.The analysis of re-positive rate of throat swab nucleic acid test in ordinary patients with COVID-19[J].Chinese Journal of Clinical Medicine,2020,27(3):366-368 |
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| Author Name | Affiliation | E-mail | | LIANG Chao | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | FEI Min | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | LING Xiao-min | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | GE Feng | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | ge.feng@zs-hospital.sh.cn | | LUO Jian-fei | Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430200, Hubei, China | rtert453@126.com | | CANG Jing | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | MIAO Chang-hong | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | |
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| Abstract:Objective: To explore the incidence and possible factors of regaining positive after pharynx swab novel coronavirus (SARS-CoV-2) nucleic acid test in patients with common novel coronavirus pneumonia (COVID-19) during hospitalization.Methods: Throat swabs of 40 patients with common COVID-19 were collected from February 2, 2020 to March 10, 2020 in the East Hospital of Renmin Hospital of Wuhan University, and SARS-CoV-2 nucleic acid was detected by real-time reverse transcriptase polymerase chain reaction (RT-PCR).Results: After the first RT-PCR test was negative in all patients, 12 cases (30%) were positive in the second RT-PCR test, 13 cases (32.5%) were positive in the third time after two consecutive RT-PCR tests were negative, and 3 cases (7.5%) were positive in the fourth time in 3 consecutive RT-PCR test negative patients. Among the patients who were negative for 4 consecutive RT-PCR tests, 0 patients were positive for the fifth time.Conclusions: As an important indicator of diagnosis and discharge of COVID-19 patients, pharyngeal swab nucleic acid test has a certain false negative rate. |
| keywords:COVID-19 SARS-CoV-2 throat swab nucleic acid RT-PCR |
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