| The analysis of anti-sperm antibody and semen quality in microsurgical varicocelectomy |
| Received:May 23, 2019 Revised:August 14, 2019 Click here to download the full text |
| Citation of this paper:yuanhaichuan,songwu,guchaohui,lilianhong,luochengpeng.The analysis of anti-sperm antibody and semen quality in microsurgical varicocelectomy[J].Chinese Journal of Clinical Medicine,2019,26(5): |
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| Author Name | Affiliation | E-mail | | yuanhaichuan | Renhe hospital, Baoshan district, Shanghai | rhyymnwk@163.com | | songwu* | Renhe hospital, Baoshan district, Shanghai | songwu021@126.com | | guchaohui | Renhe hospital, Baoshan district, Shanghai | | | lilianhong | Renhe hospital, Baoshan district, Shanghai | | | luochengpeng | Renhe hospital, Baoshan district, Shanghai | |
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| Abstract:Objective: To analyze the anti-sperm antibody and semen quality in microsurgical varicocelectomy. Methods: 67 varicocele patients treated by microsurgical varicocelectomy on our hospital from Jan. 2015 to Dec. 2017 were enrolled in the study. 67 cases were enrolled in the control group in the same period. AsAb positive rate, sperm volume, sperm concentration, sperm motility, rate of sperm with forward movement, spermSabnormalitySrate were comparatively analyzed before surgery, 3rd month after surgery, the 6th month and the 12th month. Results: There is statistical difference of AsAb positive rate and semen quality between control group and preoperative (P<0.05). AsAb positive rate of postoperative 6 months and postoperative 12 months reduced comparedSwithSthatSpreoperative (P<0.05). There is no difference about AsAb positive rate between postoperative 3 months and preoperative (P>0.05). There was no difference about sperm volume in control group, postoperative and preoperative (P >0.05). There is statistical difference of sperm concentration, sperm motility, spermSabnormalitySrate and forward movement spermSrate between postoperative 3 months and preoperative, postoperative 6 months and preoperative, postoperative 12 months and preoperative(P<0.05). 6, 12 months after surgery, sperm concentration and sperm motility improved (P<0.05). There was no difference of sperm concentration and sperm motility between postoperative 6 months and postoperative 3 months. There is no difference of spermSabnormalitySrate in postoperative 12 months, postoperative 6 months, postoperative 3 months(P>0.05). And there is a remarkable improvement of the rate of sperm with forward movement between postoperative 6 months and postoperative 3 months, postoperative 12 months and postoperative 3 months (P<0.05). There is no difference of the rate of sperm with forward movement between postoperative 12 months and postoperative 6 months (P>0.05). Pearson correlation was used to analyze the correiation between semen quality and AsAb positive rate. Conclusion: microsurgical varicocelectomy can reduce AsAb positive rate, improve semen quality in treatment of patients with varicocele. The Pearson correlation quotieties showed that sperm concentration and sperm motility are both positive correlated with AsAb positive rate. |
| keywords:varicocele anti-sperm antibody microsurgery semen quality |
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