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Cause analysis of early allograft nephrectomy after renal transplantation
Received:May 21, 2019  Revised:April 16, 2021  Click here to download the full text
Citation of this paper:WANG Xun,WANG Xuan-chuan,RONG Rui-ming,XU Ming,JI Yuan,ZHU Tong-yu.Cause analysis of early allograft nephrectomy after renal transplantation[J].Chinese Journal of Clinical Medicine,2021,28(3):482-484
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Author NameAffiliationE-mail
WANG Xun Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China
Department of Urology, Jinshan Hospital, Fudan University, Shanghai 201508, China 
 
WANG Xuan-chuan Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China wang.xuanchuan@zs-hospital.sh.cn 
RONG Rui-ming Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China  
XU Ming Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China  
JI Yuan Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China  
ZHU Tong-yu Department of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China  
Abstract:Objective: To explore the causes of early allograft nephrectomy after renal transplantation. Methods: From 2008 to 2018, 20 patients with early nephrectomy were selected from Zhongshan Hospital, Fudan University. The data of graft nephrectomy time, clinical features, auxiliary examination results, and postoperative pathology results were collected, and the causes of early graft nephrectomy were analyzed. Results: The median time of allograft nephrectomy after renal transplantation in 20 patients was 9.5 (0-77) days. Color Doppler ultrasound results showed that the blood flow was sparse and the resistance index was higher in the allograft renal. Postoperative pathology showed that 10 (50%) patients had arterial or venous thrombosis in the allograft renal, 5 (25%) patients had rejection, 2 (10%) patients had hemorrhage, 2 (10%) patients, 1 (5%) patient had primary non-function of the allograft renal. Among the 20 patients, 9 patients received donation after citizen death (DCD) donor kidneys, 2 of whom were given allograft nephrectomy due to infection. The pathogens were Acinetobacter baumannii and Mucor. Conclusions: The main cause of early allograft nephrectomy is renal thrombosis and acute rejection, and infection is one of the causes of early nephrectomy for DCD kidney transplantation.
keywords:allograft nephrectomy  resistance index  thrombosis  rejection  infection
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