| The progress of chimeric antigen receptor-T cell immunotherapy in the treatment of melanoma |
| Received:May 13, 2019 Revised:October 08, 2019 Click here to download the full text |
| Citation of this paper:DENG Xin-yi,GU Jian-ying.The progress of chimeric antigen receptor-T cell immunotherapy in the treatment of melanoma[J].Chinese Journal of Clinical Medicine,2019,26(6):942-945 |
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| Abstract:The application of chimeric antigen receptor-T cell (CAR-T) cells is a promising cellular immunotherapy in oncotherapy recent years. Gratifying results have been achieved in the treatment of hematologic malignancies such as B-lymphocytic leukemia by using CAR-T cells, but considerable difficulties still need to be overcome in the treatment of solid tumors. This review mainly discusses the principle, application, as well as the side effects of CAR-T cells therapy. |
| keywords:Chimeric antigen reporter T cell melanoma tumor immunotherapy |
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