| Clinical study on coagulation parameters and gestational outcomes of pregnant women with high normal blood pressure |
| Received:March 19, 2019 Revised:July 26, 2019 Click here to download the full text |
| Citation of this paper:SUN Ting,XU Ming-juan.Clinical study on coagulation parameters and gestational outcomes of pregnant women with high normal blood pressure[J].Chinese Journal of Clinical Medicine,2019,26(6):880-884 |
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| Author Name | Affiliation | E-mail | | SUN Ting | Department of Obstetrics and Gynecology, Changhai Hospital, Navy Military Medical University, Shanghai 200433, China
Department of Obstetrics and Gynecology, Maternal and Child Health Hospital of Songjiang District, Shanghai 201620, China | | | XU Ming-juan | Department of Obstetrics and Gynecology, Changhai Hospital, Navy Military Medical University, Shanghai 200433, China | 13636373419@163.com |
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| Abstract:Objective: To investigate the coagulation parameters and pregnancy outcomes of pregnant women with high normal blood pressure. Methods: The clinical data of 1500 pregnant women who were antenatalcared and delivered in our hospital from 2015 to 2017 were retrospectively analyzed. All of the women were divided into three groups with 500 women in each group:high normal blood pressure group, normal blood pressure group, and hypertensive disorders of pregnancy (HDP) group. The general clinical data, platelet count (PLT), mean platelet volume (MPV), platelet distributing width (PDW), thrombin time (TT), prothrombin time (PT), activated partial thromboptastin time (APTT), and fibrinogen (FIB) in third trimester, and pregnancy outcome were analyzed. Results: There were significant differences between the high normal blood pressure group and the normal blood pressure group in gravidity, parity, birth order, pre-pregnancy body mass index (BMI), gestational weight gain (GWG), PT, FIB in third trimester and cesarean section rate (P<0.05). There were significant differences between the high normal blood pressure group and the HDP group in pre-pregnancy BMI, PLT, MPV, PDW, PT, APTT in third trimester, placental abruption, postpartum hemorrhage, cesarean section rate, preterm birth, oligohydramnios, small for gestation age, and fetal distress (P<0.05). Conclusions: Some coagulation indexes of pregnant women with high normal blood pressure have changed, except for the increase of cesarean section rate, adverse pregnancy outcomes have not significantly increased, and generally high normal blood pressure pregnant women need not be included in the management of hypertensive disorders of pregnancy. |
| keywords:high normal blood pressure hypertensive disorder complicating pregnancy coagulation parameters gestational outcomes |
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