| The value of gadoxetic acid-enhanced magnetic resonance imaging for predicting recurrence of small hepatocellular carcinoma after resection |
| Received:September 25, 2019 Revised:October 29, 2019 Click here to download the full text |
| Citation of this paper:YANG Chun,WANG Wen-tao,ZENG Meng-su,RAO Sheng-xiang,ZHOU Guo-feng.The value of gadoxetic acid-enhanced magnetic resonance imaging for predicting recurrence of small hepatocellular carcinoma after resection[J].Chinese Journal of Clinical Medicine,2019,26(6):839-843 |
| Hits: 1990 |
| Download times: 634 |
| Author Name | Affiliation | E-mail | | YANG Chun | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | | | WANG Wen-tao | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | | | ZENG Meng-su | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | | | RAO Sheng-xiang | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | | | ZHOU Guo-feng | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | zhou.guofeng@zs-hospital.sh.cn |
|
| Abstract:Objective: To predict the postoperative recurrence of hepatocellular carcinoma (HCC) by using morphological and quantitative features of gadoxetic acid-enhanced magnetic resonance imaging (MRI). Methods: It was a retrospective study that included 88 patients with preoperative gadoxetic acid-enhanced MRI and confirmed as HCC (less than 3 cm in diameter) by histology. Multivariate analysis was used to screen significant imaging features associated with recurrence. Results: In the quantitative analysis, the postcontrast relative intensity ratio (RIR) and the contrast enhancement ratio (CER) of HCC were significantly correlated with the grade of HCC and postoperative recurrence (P<0.05). In the multivariate Cox regression analysis, irregular tumor border during the hepatobiliary phase (HR=4.07, P=0.001) and lower tumor CER (HR=0.97, P=0.014) were independently associated with tumor recurrence. In patients with irregular tumor border, the recurrence rate was higher than those with smooth tumor border (P=0.002). In patients with lower CER, the recurrence rate was higher than that in patients with higher CER (P<0.001). Conclusions: For gadoxetic acid-enhanced MRI, the irregular tumor border during the hepatobiliary phase and lower tumor contrast enhancement rate are significantly associated with postoperative recurrence of HCC patients. |
| keywords:hepatocellular carcinoma Gd-EOB-DTPA recurrence magnetic resonance imaging |
| HTML View Full Text View/Add Comment Download reader |
|
|
|