| Evaluation of endometrial-subendometrial blood flow measured by transvaginal ultrasound in hormone replacement cycle on outcome of embryo transplantation |
| Received:March 19, 2019 Revised:November 01, 2019 Click here to download the full text |
| Citation of this paper:ZOU Xu-tong,WANG Lin,LIU Yang,XU Jun,JI Xiao-wei,CHE Qi,DONG Xi.Evaluation of endometrial-subendometrial blood flow measured by transvaginal ultrasound in hormone replacement cycle on outcome of embryo transplantation[J].Chinese Journal of Clinical Medicine,2020,27(1):79-82 |
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| Author Name | Affiliation | E-mail | | ZOU Xu-tong | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | WANG Lin | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | LIU Yang | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | XU Jun | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | JI Xiao-wei | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | CHE Qi | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | DONG Xi | Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China | dong.xi@zs-hospital.sh.cn |
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| Abstract:Objective: To explore the value of the intrauterine thickness, endometrial-subendometrial blood flow detected by transvaginal ultrasound at endometrial transformation day in the evaluation of pregnancy outcome in infertility patients underwent embryo transplantation in hormone replacement cycle. Methods: The data of 100 patients underwent embryo transplation (ET) with hormone cycle control membrane were retrospectively analyzed. The patients were divided into pregnancy group (n=60) and non-pregnancy group (n=40). The endometrial thickness, endometrial-subendometrial blood flow indexes such as pulsatility index (PI), resistance index (RI), ratio of systolic peak velocity and end-diastolic velocity (S/D) were detected at the day of endometrium transformation. According to the result of pregnancy outcome, all patients were divided into pregnancy group and non-pregnancy group, and the differences in the various parameters between the two groups were compared. Results: There was no significant difference between the levels of estradiol (E2), luteinizing hormone (LH), follicular stimulating hormone (FSH), and the number of high-quality embryos between the two groups at transformation day. There was no significant difference in endometrial thickness between the two groups at transformation day. Compared with the non-pregnancy group, the endometrial-subendometrial hemodynamic parameters such as PI, RI, and S/D in the pregnancy group were significantly reduced at transformation day (P<0.05). The pregnancy rate was significantly lower in patients with endometrial thickness <8 mm than those of endometrial thickness ≥ 8 mm at the transformation day (P<0.05). The proportion of patients with S/D>3 in the pregnancy group was significantly lower than that in the non-pregnancy group at the transformation day (P<0.05). Conclusions: The endometrial thickness, endometrial-subendometrial blood flow detected at endometrial transformation day by transvaginal ultrasound are helpful to predict the outcome of embryo transplantation in hormone replacement cycle. |
| keywords:transvaginal ultrasound endometrial-subendometrial blood flow hormone replacement cycle embryo transplantation endometrial receptivity pregnancy outcome |
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