Research progress of glucagon-like peptide in osteoporosis |
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Citation of this paper:.Research progress of glucagon-like peptide in osteoporosis[J].Chinese Journal of Clinical Medicine,2018,25(6):997-1002 |
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Abstract:In recent years, the role of glucagon-like peptide (GLP) in osteoporosis has been discovered. GLP-1 can not only increase insulin secretion, but also promote bone formation and inhibit bone resorption. GLP-2 can not only improve the intestinal barrier and promote the absorption of nutrients, but also inhibit bone resorption. This article reviews the recent studies on the regulation of GLP-1 and GLP-2 on bone metabolism, and focuses on the potential therapeutic effects of GLP-1 and GLP-2 and their related drugs on osteoporosis, with a view to exploring new ideas for the diagnosis and treatment of osteoporosis. |
keywords:osteoporosis glucagon-like peptide 1 glucagon-like peptide 2 |
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