Research progress on molecular typing and molecular markers of colorectal cancer |
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Citation of this paper:PAN Wei-yu1, YAO Jun-xia1*, HOU Ying-yong2.Research progress on molecular typing and molecular markers of colorectal cancer[J].Chinese Journal of Clinical Medicine,2019,26(1):111-116 |
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Author Name | Affiliation | PAN Wei-yu1, YAO Jun-xia1*, HOU Ying-yong2 | 1. Department of Pathology, Qingpu Branch, Zhongshan Hospital, Fudan University, Shanghai 201700, China
2. Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China |
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Abstract:Colorectal cancer (CRC) is a highly heterogeneous tumor, and its molecular typing is helpful for the identification of the tumor histological origin, prediction of tumor progression or the risk of metastasis and recurrence, and it’s a necessary prerequisite for individualized precise treatment. The molecular markers RAS, BRAF, PI3KCA, and HER-2 could assist in the diagnosis, clinical staging, prognosis, and clinical treatment of CRC. This article reviews the recent research on molecular typing and molecular markers of CRC. |
keywords:colorectal cancer molecular type molecular marker |
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