| Corneal topography for evaluation of tear film stability in dry eye patients |
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| Citation of this paper:ZHOU Li-wen1, XIE Yu-xiu1, YUAN Fei2*.Corneal topography for evaluation of tear film stability in dry eye patients[J].Chinese Journal of Clinical Medicine,2019,26(1):69-71 |
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| Author Name | Affiliation | | ZHOU Li-wen1, XIE Yu-xiu1, YUAN Fei2* | 1. Department of Ophthalmology, Qingpu Branch, Zhongshan Hospital, Fudan University, Shanghai 201700, China
2. Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai 200032, China |
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| Abstract:Objective：To explore the surface regularity index (SRI), surface asymmetry index (SAI), cyclinder (CYL), potential visual acuity (PVA) using corneal topography and analyze their correlations with the stability of tear film. Methods：Cross-sectional and observational study was performed. Sixty dry eye outpatients (113 eyes) diagnosed with dry eye disease at the Qingpu Branch, Zhongshan Hospital, Fudan University were enrolled as dry eye group, and 33 (60 eyes) healthy volunteers were selected as control group. Tear film break-up time (BUT) examination, Schirmer’s test (ST), and the SRI, SAI, CYL, PVA tests of corneal topography were performed in both groups. Results：BUT and ST values in the dry eye group were significantly smaller than those in the control group (both P<0.05). The values of SRI, SAI, CYL in the dry eye group were significantly higher than those in the control group (all P<0.05), whereas the PVA value was smaller than that in the control group (P<0.05), with the increase of SRI, SAI and CYL values, PVA values decreased. The CYL value in the dry eye group was higher than that in the control group (P<0.05), whereas the K values of corneal topography were not significantly correlated between the two groups. Conclusions：The corneal topography parameters could reflect the stability of tear film, and be helpful for the clinical evaluation of tear film reconstruction in dry eye patients. Meanwhile, corneal topography has the advantages of objectivity, non-invasiveness and good repeatability, therefore it might play an important role in the evaluation of tear film stability in dry eye patients. |
| keywords:corneal topography tear film dry eye |
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