| The role of radical surgery in treatment of limited-stage primary small cell carcinoma of the esophagus based on clinical data of single center in China |
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| Citation of this paper:XU Zhi-yuan△, LU Chao-jing△, LI Chun-guang, WANG Xiao-wei, JIN Hai, YANG Li-xin, CHEN He-zhong, ZHU Ji*.The role of radical surgery in treatment of limited-stage primary small cell carcinoma of the esophagus based on clinical data of single center in China[J].Chinese Journal of Clinical Medicine,2018,25(2):199-202 |
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| Author Name | Affiliation | | XU Zhi-yuan△, LU Chao-jing△, LI Chun-guang, WANG Xiao-wei, JIN Hai, YANG Li-xin, CHEN He-zhong, ZHU Ji* | Department of Thoracic Surgery, Changhai Hospital, Naval Military Medical University, Shanghai 200433, China |
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| Abstract:Objective：To investigate the clinical experience of radical surgery in treatment of limited-stage primary small cell carcinoma of the esophagus (PSCCE), and to optimize the treatment strategy of PSCCE. Methods：This retrospective study was designed to investigate the clinical characteristics of 30 PSCCE patients from October 1, 2010 to July 31, 2017 in Department of Thoracic Surgery, Changhai Hospital, Naval Military Medical University. The data of treatment and follow-up were analyzed in order to summarize the treatment experience. Results：The accuracy rate of preoperative gastroscopy pathological diagnosis was 13.33% (4/30), and 80% (24/30) was performed operation combined with chemotherapy. Three cases had postoperative complications, but all the patients were discharged successfully. The 1-, 2-, and 3-year average overall survival rate of 30 patients were 54.8%, 35.1%, and 26.4%, respectively. The multivariate analysis showed that lymph node metastasis was an independent prognostic factor for the patients with PSCCE. Conclusions：The choices of treatment for PSCCE remain uncertain, surgical resection combined with chemotherapy is effective for patients with PSCCE. The patients with lymph node metastasis may not benefit from radical surgery. |
| keywords:esophageal neoplasms carcinoma, small cell surgical procedures, operation prognosis |
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