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Research progress in clinical application of cerebral tissue oxygen saturation
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Citation of this paper:TIAN Peng-sheng1, MA Hong-chang2.Research progress in clinical application of cerebral tissue oxygen saturation[J].Chinese Journal of Clinical Medicine,2019,26(2):292-296
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Author NameAffiliation
TIAN Peng-sheng1, MA Hong-chang2 1. Center of Anesthesia, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100037, China 2.Department of General Surgery, Gaobeidian Yanzhao Hospital, Baoding 074099, Hebei, China 
Abstract:Cerebral tissue oxygen saturation (SctO2) monitor can monitor SctO2 noninvasively and continuously. SctO2 reflects the equilibrium state of oxygen supply and oxygen consumption in the brain tissue. Many factors can affect SctO2, such as cardiopulmonary dysfunction, cerebral tissue perfusion and metabolism, changes of blood components and pH, the physiological and pathological changes of intracranial vessels, drug, changes in body temperature and body metabolism, changes in body position and oxygen inhalation concentration during the operation. Therefore, SctO2 changes can be caused by diseases, clinical interventions, and surgery methods that can affect the above factors. Low SctO2 in the perioperative period can cause postoperative neurocognitive dysfunction (POCD), postoperative nausea and vomiting (PONV), delirium, and other complications. This article reviews the application of SctO2 in cardiac macrovascular surgery, carotid endarterectomy, single lung ventilation, orthopedic surgery, and Pediatrics, in order to provide reference for the clinic value and further research of SctO2.
keywords:cerebral tissue oxygensaturation  postoperative cognitive dysfunction  postoperative nausea and vomiting  Pediatrics department
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