| Abstract:Objective：To compare the clinical effect between hemi-semi-laminectomy and hemilaminectomy approach for treatment of spinal schwannomas. Methods：Clinical data of patients with spinal schwannomas who underwent microsurgical treatment were retrospectively analyzed, among them, 24 cases for hemi-semi-laminectomy approach and 30 cases for hemilaminectomy approach. The duration of operation, intraoperative blood loss, postoperative complications, spinal stability, stay time and costs of hospitalization were compared between two groups. Results：The tumors were totally removed, and the symptoms and signs were improved significantly after operation in both groups. Compared with hemilaminectomy approach group, hemi-semi-laminectomy approach group had shorter operation duration, less intraoperative blood loss, shorter hospitalization stay and lower costs (all P<0.05). However, there were no significant differences in incidences of complications or spinal deformity between two groups. Conclusions：Hemi-semi-laminectomy approach can achieve a further reduction in iatrogenic trauma compared with hemilaminectomy approach without increasing surgical risk and incidences of complications, which is a safe and effective approach for microsurgical treatment of spinal schwannomas between two vertebral plates. |