| Research progresses on ubiquitin-specific protease 15 |
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| Citation of this paper:SONG Jian-xiang1*, YI Zhong-quan2, ZHENG Shi-ying3.Research progresses on ubiquitin-specific protease 15[J].Chinese Journal of Clinical Medicine,2018,25(2):296-299 |
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| Author Name | Affiliation | | SONG Jian-xiang1*, YI Zhong-quan2, ZHENG Shi-ying3 | 1. Department of Cardiothoracic Surgery, the Affiliated Yancheng Hospital of Southeast University Medical College, Yancheng 224001, Jiangsu, China
2. Central Laboratory, the Affiliated Yancheng Hospital of Southeast University Medical College, Yancheng 224001, Jiangsu, China
3. Department of Cardiothoracic Surgery, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu, China |
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| Abstract:Ubiquitin-specific protease 15 (USP15), a member of the deubiquitinating enzyme family, belongs to cysteine protease. Recent studies have revealed that USP15 can mediate the regulation of stability and function of various cellular proteins directly or indirectly, and exert an influence on the occurrence and development of tumor and many other diseases. Therefore, USP15 may become a potential molecular target for treating related diseases. This article summarized the recent research progresses of USP15 on its gene localization and expression and relationship with related diseases. |
| keywords:USP15 tumor signaling pathway molecular target |
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