| Abstract:Objective：To explore the risk factors of paroxysmal atrial fibrillation (PxAF) in patients with cryptogenic stroke (CS). Methods：Totally 340 cases of inpatients with ischemic stroke from March 2015 to February 2017 underwent cardiac and vascular ultrasound, blood routine examination, conventional coagulation examination, detection of blood lipid, and blood glucose, head CT, head MRI+DWI, head and neck MRA and (or) CTA, etc. These patients were divided into CS group, PxAF related stroke group, and permanent atrial fibrillation (PermAF) related stroke group, based on the past medical history, 12-channel electrocardiogram in admission and 24 or 72 h Holter in the first 7 days of admission. The clinical features of PxAF related stroke and the risk factors of PxAF in CS patient were analyzed. Results：There were 251 of CS, 45 of PxAF related stroke, and 44 of PermAF related stroke in total 340 cases; the modified Ranking Scale/score (mRS) and the death rate 3-6 months after discharge had no statistical significance between PxAF related stroke group and PermAF related stroke. Multi-factor Logistic analysis showed that the age (OR=1.142, 95%CI 0.017-1.065), National Institute of Health stroke scale (NIHSS) on admission (OR=1.351, 95%CI 1.035-1.763), score for the targeting of atrial fibrillation (STAF) (OR=3.945, 95%CI 1.650-9.431), frequent atrial premature beats (OR=8.034, 95%CI 1.014-63.646), left atrial dimension (OR=1.452, 95%CI 1.109-1.901), infarct number, left and right side both being involved were the independent risk factors of PxAF in CS patients (P＜0.05). Conclusions：For CS patients with older age, higher NIHSS score on admission, higher STAF score, frequent atrial premature beats, larger left atrial dimension, more infarctions, left and right side both being involved, ECG detection time should be prolonged so as to detect PxAF timely. |