| Abstract:Objective：To investigate the effect of preoperative nutrition assessment and intervention on the curative effect of gastric cancer surgery. Methods：Totally 105 patients with gastric cancer were included in the Department of General Surgery of the First Affiliated Hospital of Hebei North University for radical gastrectomy of gastric cancer.The preoperative nutrition assessment was performed with Nutrition Risk Screening 2002 (NRS 2002)—the patients with greater than or equal to 3 points had nutritional risk (the nutritional risk group, n=43 ) and the patients with less than 3 points had normal nutrition (the non-nutritional risk group, n=62). The two groups were further divided into the nutrition support subgroup and the non-nutrition support subgroup. The postoperative recovery (first exhaust time, first defecation time, first ambulation, and average hospitalization time), nutrition, immune function, and complications were compared. Results：In the nutritional risk group, the first exhaust time, first defecation time, and first ambulation time of patients in the nutrition support group were significantly earlier than those in the non-nutrition support group, and the differences were statistically significant (P<0.05). The average length of hospitalization of the patients in the nutrition support group was significantly earlier than that in the non-nutrition support group, and the difference was statistically significant (P<0.001). In the non-nutritional risk group, there was no significant difference in the postoperative recovery between the two subgroups. In the nutritional risk group, serum prealbumin (PAB), transferrin (TRF), and albumin (ALB) of patients in the nutrition support group on the fifth day after operation were significantly higher than those in the non-nutrition support group, and the differences were statistically significant (P<0.05). There was no significant difference in the above indexes between the two subgroups of the non-nutritional risk group. In the nutritional risk group, IgA, IgG, IgM, CD3+, CD4+, and CD4+/CD8+ of patients in the nutrition support group on the fifth day after operation were significantly higher than those in the non-nutrition support group, and the differences were statistically significant (P<0.05). There was no significant difference in the above indexes between the two subgroups of the non-nutritional risk group. In the nutritional risk group, the incidence of complications was 10.34% in the nutrition support group, which was significantly lower than that 35.71% in the non-nutrition support group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of complications between the two subgroup of the non-nutritional risk group. Conclusions：Preoperative nutritional assessment of patients with gastric cancer and targeted nutritional support can significantly improve the nutritional status and immune function, reduce postoperative complications, and promote recovery. |