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Citation of this paper:.[J].Chinese Journal of Clinical Medicine,2017,24(4):650-655
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卫传元,顾建英* 复旦大学附属中山医院整形外科上海200032 
Abstract:Chronic wound is a major challenge in plastic surgery and the whole medical field. The way to promote wound healing is a matter to be solved urgently. Adipose derived stem cells (ADSCs), compared to other mesenchymal stem cells,have the advantages of convenient material, adequate source and poise sculpture, and have become a hotspot in the field of regenerative medicine in recent years. A large number of studies have shown that ADSCs can promote chronic wound healing through a variety of mechanisms and are considered to be a promising treatment strategy. In this paper, the isolation and purification, the mechanism and application of ADSCs in chronic wounds were reviewed.
keywords:chronic wound  adipose derived stem cells  paracrine  induced differentiation
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