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Diagnostic value of subtraction coronary computed tomography angiography in patients with mild-moderate calcification score
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Citation of this paper:.Diagnostic value of subtraction coronary computed tomography angiography in patients with mild-moderate calcification score[J].Chinese Journal of Clinical Medicine,2018,25(1):35-39
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Author NameAffiliation
张利军1,2, 过伟锋1,3, Tripathi Pratik1, 杨姗1,2, 陆怡菡1, 陈刚1* 1. 复旦大学附属中山医院放射诊断科上海 200032 2. 复旦大学附属中山医院厦门医院放射科厦门 361010 3. 上海市影像医学研究所上海 200032 
Abstract:Objective:To investigate the clinical diagnostic value of subtraction coronary computed tomography angiography (CCTA) in patients with mild-moderate calcification of coronary artery (Agatston score<400). Methods:A retrospective analysis of 69 cases with mild-moderate coronary calcification undergoing subtraction CCTA was performed. The image quality of calcified segments was evaluated using 4-point scale method. The stenosis of calcified segment was quantitatively assessed and divided into four different classifications (Ⅰ-Ⅳ). The time for quantitative assessment of calcified segments was recorded. Results:〖JP2〗There were 113 calcified segments in 69 cases. The average image quality of calcified segments for conventional CCTA and subtraction CCTA was (3.4±0.6) and (3.8±0.4), respectively, with significant difference (P<0.01). The Kappa coefficient used to describe the consistency of the stenosis grading in these two imaging methods was 0.77. The average time needed for quantitative assessment was (105±44) s and (72±44) s, respectively, with significant difference (P<0.01). Conclusions:The two imaging methods have good consistency in evaluating stenosis grading in patients with mild-moderate calcification of coronary artery. Compared with conventional CCTA, subtraction CCTA can improve the image quality and reduce the time required for quantitative assessment of stenosis, thus improve the clinical efficiency.
keywords:coronary heart disease  vascular calcification  subtraction technique  coronary computed tomography angiography
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