| Abstract:Objective：To observe the effect of oral liquid carbohydrates (1,000 mL of liquid carbohydrates 12h before operation, and 500 mL of liquid carbohydrates 2h before operation) based on enhanced recovery after surgery (ERAS) on gastric contents reflux aspiration and hemodynamics during general anesthesia induction in patients undergoing gastric cancer surgery. Methods：60 patients with ASA grade Ⅰ to Ⅱ and 35-70 years old who underwent laparoscopic radical gastrectomy were randomly divided into two groups: routine fasting group (group G), and preoperative oral liquid carbohydrate group (group E), with 30 cases in each group. Patients in group E took 1 000 mL of liquid carbohydrates 12 h before operation, and 500 mL of liquid carbohydrates 2 h before operation. Both groups of patients were given propofol combined with remifentanil target controlled intravenous and injection of cisatracurium in anesthesia induction. HR, BIS, MAP, CO, CI, and SVV were recorded before induction (T0), just before intubation (T1), 1 min (T2), 3 min (T3), 5 min (T4), 10 min (T5), and 20 min (T6) after induction. Gastric contents reflux aspiration during general anesthesia induction and gastric residual liquid capacity were also observed. Results：HR, BIS, MAP, CO, CI of both groups at T1 were significantly lower than those at T0 (P<0.05). SVV of group E at T2-T6 were lower than those of group G (P<0.05), and MAP, CO, and CI of group E at T1-T6 were higher than those of group G (P<0.05). There was no regurgitation aspiration in both groups during anesthesia induction. There was no significant difference between the two groups in gastric residual liquid capacity. Conclusions：Preoperative oral rehydration (1 000 mL of liquid carbohydrates 12 h before operation, and 500 mL of liquid carbohydrates 2 h before operation) based on ERAS can better maintain hemodynamic stability during induction of general anesthesia in patients undergoing elective gastric cancer surgery, without increasing the gastric residual liquid capacity and the risk of reflux aspiration. |