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Value of susceptibility-weighted imaging in diagnosing Parkinson disease
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Citation of this paper:.Value of susceptibility-weighted imaging in diagnosing Parkinson disease[J].Chinese Journal of Clinical Medicine,2018,25(1):87-89
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Author NameAffiliation
马松华1△, 邹丽2△, 王小乐3*, 邵雅楠1, 江齐群1, 张玲玲1, 陆健美3 1. 南通市第二人民医神经内科南通 226002 2. 如皋市人民医院神经内科如皋 226500 3. 南通市第二人民医院影像科南通 226002 
Abstract:Objective:To evaluate the value of susceptibility-weighted imaging(SWI) in diagnosis of Parkinson disease (PD) and assessment of disease severity. Methods:Totally 30 PD patients and 30 healthy volunteers underwent SWI. The phase values of nuclei in extracorticospinal tract were measured and compared between PD patients and healthy subjects. Results:The phase values of sustantia nigra pars compacta, globus pallidus, putamen in PD group were all significantly lower than those in control group(P<0.01). The phase values of sustantia nigra pars compacta, globus pallidus and putamen reduced at the early stage in PD group, and then further reduced along with the severity of disease(P<0.05). Conclusions:SWI has important clinical value in diagnosing PD and evaluating the disease severity.
keywords:susceptibility-weighted imaging  Parkinson disease  phase value
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