| Abstract:Objective：To investigate the clinical effect of dexmedetomidine in ultrasound guided brachial plexus block.
Methods：Totally 60 cases with ultrasound guided brachial plexus block in Affiliated Hospital of Nantong University were divided into experimental group and control group, with 30 cases in each group. The ropivacaine 75 mg were given to the control group, while ropivacaine 75 mg+ dexmedetemidine 1.0 μg/kg were used in experimental group. The HR, MAP, SpO2, Ramsay score at the time of entering the operating room (T0), brachial plexus anesthesia 10 min (T1), beginning of the operation (T2), 30 min after the start of operation (T3), at the end of the surgery (T4) were compared in two groups, while sensory and motor block work time, length of time, length of analgesia were recorded. Adverse effects were also observed and recorded.
Results：The MAP, HR at T1, T2 in experimental group were lower than those in T0 , and lower than those in the control group significantly(P＜0.05). The Ramsay score in experimental group was lower than that in the control group at each time point significantly (P＜0.05).Sensory blockade working time, motion block work time in experimental group were shorter than those in control group significantly(P＜0.05), while the sensory blockade maintenance time, motion block maintain time and duration time of analgesia in experimental group were longer than those in control group (P＜0.05). There was no statistically significant differences in adverse effects between the groups.
Conclusions：Dexmedetomidine combined with ropivacaine in ultrasound guided brachial plexus block can shorten onset time of local anaesthesia, prolong the duration of sensory block, motor block, and duration of analgesia. |