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Clinical Analysis of Hyperglycemic Hyperosmolar Nonketotic Coma after Esophagectomy
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Citation of this paper:CHEN Ying,LIN Zongwu,XU Songtao,WANG Qun.Clinical Analysis of Hyperglycemic Hyperosmolar Nonketotic Coma after Esophagectomy[J].Chinese Journal of Clinical Medicine,2016,23(1):31-33
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Author NameAffiliationE-mail
CHEN Ying Department of Thoracic Surgery, Gaozhou People's Hospital, Gaozhou 525200, China  
LIN Zongwu Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China lin.zongwu@zs-hospital.sh.cn 
XU Songtao Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
WANG Qun Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
Abstract:Objective: To explore the etiology, as well as the clinical prevention and treatment strategy, of hyperglycemic hyperosmolar nonketotic coma after esophagectomy. Methods: The clinical data of five patients who suffered hyperglycemic hyperosmolar nonketotic coma after esophagectomy in Department of Thoracic Surgery, Zhongshan hospital, Fudan Unviersity during January 2009 and December 2014, were retrospectively analyzed. Results: There was no case with diabetes history among the five cases before operation. All the 5 cases received enteral nutrition after operation, among which 4 cases suffered postoperative complications. The main symptoms included dehydration and psychogenia. And coma occurred in severe cases. Three cases recovered well and reach an average hospital stay of 42 days owning to early diagnosis and treatment. The other two were diagnosed too late. One case died in hospital on the 54th day after operation and the other case had been staying in hospital for 210 days. Furthermore, no patient developed diabetes. Conclusions: Hyperglycemic hyperosmolar nonketotic coma may even occur after esophagectomy in patients without diabetes, especially in the patients who suffer from complications or received enteral nutrition. Postoperative monitoring of blood glucose could prevent this complication. Early diagnosis and treatment could improve its prognosis.
keywords:Esophageal cancer  Postoperative  Complications  Hyperglycemia  Hyperosmolar nonketotic coma
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