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Citation of this paper:.[J].Chinese Journal of Clinical Medicine,2016,23(6):773-775
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Author NameAffiliation
桑江勇1,高晓东2,薛安慰2,方勇2,束平2,凌佳倩2,侯英勇3,沈坤堂2*,秦净2,孙益红2,秦新裕2 1. 新疆维吾尔自治区喀什地区第二人民医院普通外科, 喀什844000  2. 复旦大学附属中山医院普通外科上海200032 3. 复旦大学附属中山医院病理科, 上海200032 
Abstract:Objective:To investigate the recurrence factors of small intestine gastrointestinal stromal tumor (GIST) after resection. Methods:The clinicopathological data of 67 patients with recurrent small intestine GIST admitted to Zhongshan Hospital affiliated to Fudan University from January 2004 to December 2013 were retrospectively analyzed. Kaplan Meier method was used to analyze the effects of different factors on the recurrence time of small intestine GIST. Cox multi factor regression analysis was used to analyze the independent factors of recurrence of small intestine GIST. Results:Univariate analysis revealed that the median recurrence time significantly shortened in patients with tumor diameter more than 10 cm, mitotic rate greater than or equal to 30/50 HPF, tumor rupture, and R0 resection, and the difference was significant (P<0.05). Multivariate analysis demonstrated that tumor rupture and surgical methods were independent prognostic factors for the recurrence of small intestine GIST (P<0.05). Conclusions:R0 resection and intraoperative tumor rupture avoidance can prolong the recurrence time of small intestine GIST.
keywords:gastrointestinal stromal tumor  surgery  prognosis
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