Abstract: Transradial access (TRA) has become the standard approach in coronary interventional procedure, offering advantages such as minimal trauma and increased comfort compared to transfemoral access. In recent years, the use of TRA in the intervention treatment of peripheral vascular diseases has gradually gained attention. However, it still faces challenges in clinical promotion. This review comprehensively summarizes the advantages and challenges of TRA in peripheral intervention treatment, delving into its practical application based on the latest clinical research findings. Simultaneously, this review provides a prospective outlook on the future development of TRA in the field of peripheral intervention, aiming to offer valuable insights for further research and practical applications in this field.