摘要: |
自20世纪以来,以阿片类药物为基础的镇痛方案已成为全球范围内主流的镇痛方式,但阿片类药物存在一些不良反应,如便秘、呼吸抑制、阿片类药物引起痛觉过敏、阿片类药物成瘾等。为实现“舒适化医疗”,提高患者医疗体验和生存质量,镇痛药物用药方案的改良已成为临床关注的重点。本文将重点阐述阿片类药物的发展方向。 |
关键词: 阿片类药物 镇痛 精准医疗 去阿片化麻醉 术后不良反应 |
DOI:10.12025/j.issn.1008-6358.2023.20220371 |
分类号:R 9 |
基金项目:上海市临床重点专科建设项目(shslczdzk03603). |
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Application and new advance of opioids |
LAN Qin-zhou, FANG Fang, CANG Jing
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Department of Anesthesiology, Fudan University, Zhongshan Hospital, Shanghai 200032, China
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Abstract: |
Since the 20th century, opioid-based analgesia has become a global mainstream way of analgesia, but the application of opioid drugs has many disadvantages, such as constipation, respiratory depression, opioid-caused hyperalgesia, opioid-addicted, and so on. Nowadays, to achieve “comfortable medical treatment”, to improve the patients’ medical experience and the qualities of life, how to improve medication plans of analgesia has became the emphasis. This review mainly describes the development direction of opioid. |
Key words: opioid analgesics precision medicine opioid-free anesthesia postoperative adverse effects |