摘要: |
目的 应用超声三维斑点追踪技术(three-dimensional speckle tracking imaging,3DSTI)观察左室型单心室患儿Glenn手术前、后左心功能的变化。方法 对17例左室型单心室患儿于Glenn术前及术后分别进行三维超声和心脏磁共振检查,估测左心功能;术前、术后分别与年龄、性别匹配的17例健康儿童(对照组)进行比较。结果 与对照组儿童对比,左室型单心室患儿心室舒张末期容积、收缩末期容积、每搏输出量增加(P<0.01),射血分数、左心室整体纵向应变、整体环向应变、平均切向应变、平均纵向应变、平均环向应变、平均径向应变较差(P<0.01)。患儿Glenn术后左心室整体环向应变、平均环向应变、平均径向应变较术前改善(P<0.05),射血分数、左心室整体纵向应变、整体环向应变、平均切向应变、平均纵向应变、平均环向应变、平均径向应变仍差于对照组(P<0.05)。整体环向应变与磁共振估测的射血分数相关性最好(r=-0.793,P<0.001)。结论 左室型单心室患儿可伴发收缩功能不全,Glenn术后部分改善,但仍较差;3DSTI可准确评估左室型单心室患儿的心功能变化。 |
关键词: 三维超声斑点追踪技术 左室型单心室 收缩功能 Glenn术 |
DOI:10.12025/j.issn.1008-6358.2022.20211299 |
分类号:R541.1 |
基金项目:国家自然科学基金青年项目(82001835),小儿心血管(卫计委高端儿科海外研修团队)基金(GDEK201706),上海交通大学"交大之星"计划医工交叉研究基金(YG2019QNB03). |
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Evaluation of the function of single left ventricle by three-dimensional speckle tracking imaging after Glenn procedure |
ZHOU Chun-xia1, CHEN Li-jun2, ZHANG Yu-qi2, BAO Sheng-fang2
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1.Department of thoracic surgery, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China;2.Department of Cardiology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
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Abstract: |
Objective To assess the systolic function of single left ventricle before and after Glenn procedure by three-dimensional speckle tracking imaging (3DSTI). Methods Before and after Glenn procedure, the systolic function of the left ventricle was assessed by 3DSTI and cardiac magnetic resonance (CMR) in 17 children with single left ventricle, and compared with 17 age- and gender-matched healthy children (control group). Results Compared with children in the control group, end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) of children in the single left ventricle group increased significantly (P<0.01), ejection fraction (EF), global longitudinal strain (GLS), global circumferential strain (GCS), average tangential strain (TS), average longitudinal strain (LS), average circumferential strain (CS), and average radial strain (RS) were impaired (P<0.01). After the operation, GCS, CS, and RS were significantly improved (P<0.05), but EF, GLS, GCS, TS, LS, CS, and RS were still poorer than those in the control group (P<0.05). GCS was significantly correlated with EF measured by CMR (r=-0.793, P<0.001). Conclusion Single left ventricle could be accompanied by impaired ventricular systolic function, which might be partially improved by Glenn procedure, and 3DSTI is an accurate clinical tool for the assessment of ventricular systolic function. |
Key words: three-dimensional speckle tracking imaging single left ventricle systolic function Glenn procedure |