摘要: |
目的: 采用Meta分析方法评价光电联合治疗缓解面部皱纹的效果。方法: 检索中国知网、万方科技期刊全文数据库、PubMed和Web of Science建库至今收录的光电联合面部抗皱的相关文献,排除重复、无对照、数据缺失的文献,并评价文献相关偏倚,使用Review Manager 5.3软件分析皱纹改善情况。结果: 共纳入13项研究,包含1 181例受试者,其中联合治疗组644例,单一方法组627例。Meta分析显示,光电联合的抗皱效果优于仅采用激光或射频等的单一策略(OR=2.25,95% CI 1.69~3.00,P<0.000 1)。在敏感性分析中,各研究对Meta分析整体影响较小。结论: 光电联合面部抗皱效果常优于单一方法,可进一步改进联合策略,并建立疗效评估标准,同时须进一步对面部皱纹分类论证。 |
关键词: 光电联合治疗 面部皱纹 meta分析 |
DOI:10.12025/j.issn.1008-6358.2021.20202472 |
分类号:R622 |
基金项目:国家自然科学基金(81972559). |
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Meta-analysis of combined photoelectric therapy for facial wrinkles |
REN Ming, DENG Xin-yi, WEI Chuan-yuan, WANG Lu, GAO Zi-xu, GU Jian-ying
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Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
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Abstract: |
Objective: To evaluate the therapeutic effect of combined photoelectric therapy on facial wrinkles using the meta-analysis method.Methods: The literature about combined photoelectric therapy for facial wrinkles was searched in databases including CNKI, Wanfang data, PubMed, and Web of Science, studies that were duplicated, had no control group, or had missing data were excluded. The literature-related bias was evaluated, and the indexes of efficacy for wrinkles were analyzed by Review Manager 5.3 software.Results: A total of 13 studies were included, including 1 181 subjects and 644 in the combined treatment group and 627 in the single treatment group. According to the Meta-analysis, the effect of the combined treatment group was better than that in the single treatment group (OR=2.25, 95%CI 1.69-3.00, P<0.000 1). In the sensitivity analysis, each study has little impact on the overall meta-analysis. Conclusions: The effect of combined photoelectric therapy for facial wrinkles is often superior to single photoelectric therapy. It is necessary to improve combined photoelectric strategies, establish evaluation criteria, and take further categorical arguments. |
Key words: combined photoelectric therapy facial wrinkle meta-analysis |