摘要: |
目的:探讨强迫症(obsessive-compulsive disorder,OCD)患者应激感受水平对暴露反应预防(exposure and response prevention,ERP)疗效的影响。方法:纳入27例符合《美国精神障碍诊断与统计手册第四版》标准并接受ERP治疗的OCD患者。采用耶鲁-布朗强迫量表(Yale-Brown obsessive compulsive scale,Y-BOCS)在治疗前和治疗2周、4周和8周后评估OCD患者的强迫症状严重程度。采用应激感受量表(perceived stress scale-10,PSS-10)评估患者治疗前的应激感受水平。结果:治疗8周后,ERP治疗有效率为40.7%(11/27)。Logistic回归分析显示,治疗前应激感受水平较高的OCD患者ERP疗效较差(OR=0.83,P=0.047)。结论:ERP可能对治疗前应激感受水平高的患者效果不佳。 |
关键词: 强迫症 应激感受 暴露反应预防 |
DOI:10.12025/j.issn.1008-6358.2021.20201941 |
分类号: |
基金项目:上海市卫生健康委员会重要薄弱学科——心身医学(2019ZB0201),复旦大学附属中山医院青年基金(2019ZSQN44). |
|
Effect of perceived stress level on efficiency of exposure and response prevention in obsessive-compulsive disorder patients |
WANG Yuan1, ZHAO Qing2, WANG Zhen2
|
1.Department of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China;2.Department of Clinical Psychology, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
|
Abstract: |
Objective: To explore how perceived stress affects the efficiency of exposure and response prevention (ERP) in obsessive-compulsive disorder (OCD) patients.Methods: Twenty-seven outpatients meeting the Diagnostic and Statistical Manual of Mental Disorders (fourth edition) criteria for OCD were treated with ERP for 8 weeks. The severity of obsessive-compulsive symptoms were measured with Yale-Brown obsessive compulsive scale (Y-BOCS) at baseline, 2 weeks, 4 weeks, and 8 weeks after treatment. Perceived stress was evaluated with perceived stress scale-10 (PSS-10) before treatment.Results: The response rate of ERP was 40.7%(11/27) 8 weeks after treatment. Individuals with higher pre-treatment levels of perceived stress were less likely to be responsive to ERP (OR=0.83, P=0.047).Conclusions: ERP did not appear to be effective in patients with high level of perceived stress. |
Key words: obsessive-compulsive disorder perceived stress exposure and response prevention |