摘要: |
目的:探讨阴道超声引导下胚胎移植对反复种植失败(repeated implantation failure,RIF)患者冻融胚胎移植妊娠结局的影响。方法:回顾性分析2017年6月至2019年6月进行体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)患者中再次行冻融胚胎囊胚移植48例RIF患者的临床资料,根据胚胎移植时是否使用阴道超声引导分为实验组(24例)和对照组(24例),比较2组间的胚胎种植率、临床妊娠率及流产率。结果:实验组临床妊娠率(37.50%)和胚胎种植率(29.26%)显著高于对照组(29.16%、21.05%),差异有统计学意义(P<0.05);实验组流产率(11.11%)与对照组(14.28%)相比,差异无统计学意义。结论:采用阴道超声引导下胚胎移植可改善RIF患者的临床妊娠结局。 |
关键词: 经阴道超声 反复种植失败 冻融胚胎移植 临床妊娠率 |
DOI:10.12025/j.issn.1008-6358.2020.20192263 |
分类号:R321 |
基金项目:国家自然科学基金(81701435,81971345). |
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Effect of transvaginal ultrasound-guided embryo transfer on pregnancy outcome in patients with repeated implantation failure |
CHE Qi, LIU Su-ying, DONG Xi
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Reproduction Medicine Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China
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Abstract: |
Objective: To investigate the effect of transvaginal ultrasound-guided embryo transfer on the pregnancy outcomes of patients with repeated implantation failure (RIF). Methods: From June 2017 to June 2019, the clinical data of 48 in vitro fertilization and embryo transfer (IVF-ET) patients who underwent frozen-thawed embryo transfer again were analyzed retrospectively. According to whether the embryo transfer was guided by transvaginal ultrasound, they were divided into the experimental group (24 cases) and the control group (24 cases). The clinical embryo implantation rate, pregnancy rate, and spontaneous abortion rate between the two groups were analyzed and compared. Results: The clinical pregnancy rate (37.50%) in the experimental group and embryo implantation rate (29.26%) of the experimental group were significantly higher than those in the control group (29.16% and 21.05%, respectively), the differences were statistically significant (P<0.05); there was no statistically difference in the abortion rate between the control group (14.28%) and experimental group (11.11%). Conclusions: Transvaginal ultrasound-guided embryo transfer could improve the clinical pregnancy outcomes of RIF patients. |
Key words: transvaginal ultrasound repeated implantation failure frozen-thawed embryo transfer clinical pregnancy rate |