摘要: |
目的:探讨Guidezilla延长导管在非闭塞性冠状动脉(简称冠脉)钙化病变介入治疗中的有效性和安全性。
方法:选择2015年3月至2017年8月收治的非完全闭塞性冠脉钙化病变,由于球囊或支架输送困难,无法通过病变,在Guidezilla导管辅助下实施经皮冠状动脉介入治疗(PCI)的患者。采集人口统计学资料、病史、冠脉病变特征等信息,分析Guidezilla导管操作成功率、介入手术成功率和PCI相关并发症。
结果:共选择183例患者,冠脉病变分型为B2/C型者占比99.5%;其中,合并多支血管病变者占94.0%,合并冠脉扭曲或成角者占85.3%。因支架输送失败而使用Guidezilla延长导管者占87.4%。Guidezilla操作成功率和PCI手术成功率分别为89.6%和97.3%。操作相关并发症发生率为3.3%(6例),其中冠状动脉夹层占66.7%(4例),无致死性并发症;住院期间主要心血管不良事件(MACEs)发生率为2.2%(4例);平均12个月的随访期内,MACEs发生率为7.7%(14例)。
结论:Guidezilla延长导管能安全有效地用于非闭塞性中重度冠脉钙化狭窄病变的PCI治疗。 |
关键词: 经皮冠状动脉介入治疗 钙化 Guidezilla导管 |
DOI: |
分类号:R 543.3+1 |
基金项目:国家自然科学基金(81570317),中国中青年临床研究基金-V.G.(2017-CCA-VG-031). |
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Application of Guidezilla extension catheter during percutaneous coronary intervention for non-total occlusive calcified lesions |
ZHANG Shu-ning△, DENG Xin△, YAO Kang, GE Lei, QIAN Ju-ying, GE Jun-bo*
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Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China
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Abstract: |
Objective:To investigate the efficacy and safety of Guidezilla during percutaneous coronary intervention (PCI) for non-total occlusive calcified coronary lesions.
Methods:The patients with non-total occlusive calcified coronary lesions were collected between March 2015 and August 2017. All of them received Guidezilla-assisted PCI due to the difficulties of balloon or stent delivering. The demographic data, medical history, lesion characteristics, Guidezilla procedural success rate, PCI success rate, and PCI-related complications were recorded and analyzed.
Results:One hundred and eighty-three patients were selected. Almost all of the coronary calcified lesions (99.5%) were classified as type B2/C. Among which, 94.0% were accompanied by multi-vessel diseases and 85.3% coronary tortuosity or angulation. The majority of patients (87.4%) used Guidezilla due to difficulties of delivering stents across the calcified lesions. Guidezilla procedural and PCI success rate was 89.6% and 97.3%, respectively. The incidence of operation-related complications during PCI was 3.3% (6 cases), and among which, 66.7% (4 cases) was coronary dissection. The incidence of major adverse cardiac events (MACEs) was 2.2% (4 cases) and 7.7% (14 cases) during hospitalization and the follow-up period of 12-month, respecitively.
Conclusions:Guidezilla-assisted PCI is effective and safe in patients with non-total occlusive and moderate-severe calcified coronary lesions. |
Key words: percutaneous coronary intervention calcified lesions Guidezilla catheter |