Abstract: Objective：To evaluate the clinical efficacy of suture anchor combined with Endobutton plate in the treatment of Tossy grade Ⅲ acromioclavicular dislocation. Methods：From Feb 2011 to Dec 2015, a retrospective study was performed on 27 patients with Tossy grade III acromioclavicular joint dislocation treated by suture anchor combined with Endobutton plate (Anchor group). The clinical efficacy was assessed by visual analogue scale (VAS) and Constant-Murley score (CMS). All parameters were compared with those of 32 patients with the same disease treated by clavicular hook plate (CHP group). Results：All the 59 patients were followed up for 14 to 38 months (mean, 16.2±3.8 months). The mean operative time was (45.3±7.1) min in CHP group and (47.0±7.6) min in Anchor group, there was no significant difference between the two groups (P>0.05). VAS and CMS of the injured shoulder in Anchor group were better than those in CHP group at 3 months after operation (P<0.05). The routine removal of the plate was performed in CHP group at 3 to 6 months after operation. No significant difference was observed in VAS and CMS of the injured shoulder between the two groups at 12 months after operation (P>0.05). During the follow-up, failure of internal fixation with complete loss of reduction occurred in 1 case of Anchor group. 8 cases with subacromial impingement syndrome and 1 case with subacromial bony erosion were observed in the CHP group. The incidence of complications in the Anchor group was significantly lower than that in the CHP group (P<0.05). The medical expenses were (25 569.2±1 146.7) ￥ in Anchor group and (27 735.8±1 779.7) ￥ in CHP group, there was a significant difference between the two groups (P<0.05). Conclusions：The method of suture anchor combined with Endobutton plate in the treatment of Tossy grade Ⅲ acromioclavicular dislocation can produce satisfactory clinical results, compared with CHP, it is associated with fewer complications, lower medical expenses, less shoulder pain, and better shoulder function in the early postoperative period.