摘要: |
目的:对肥胖伴黑棘皮病患者的心理抑郁状况进行调查分析,为其临床诊治提供支持。方法:2014年3月至8月在上海市第十人民医院内分泌科门诊及住院部就诊的88例肥胖患者以及年龄匹配的56名正常体质量健康志愿者(正常对照组,n=56)参加问卷调查。88例肥胖患者分为单纯性肥胖组(n=30)及肥胖伴黑棘皮病组(n=58)。采用Beck Ⅱ抑郁问卷对3组研究对象进行测试,同时收集一般临床资料及检验指标,进行相关性分析。结果:肥胖伴黑棘皮病组患者FFA及UA高于单纯性肥胖组(P<0.05)。单纯性肥胖组及肥胖伴黑棘皮病组患者抑郁评分高于正常对照组(P<0.05),肥胖伴黑棘皮病组患者抑郁发生率为67.2%,高于单纯性肥胖组(43.4%)及正常对照组(3.6%,P<0.05)。结论:肥胖伴黑棘皮病患者代谢紊乱及抑郁状况较单纯肥胖患者更严重,在减重的同时需要积极干预患者的抑郁状态。 |
关键词: 肥胖 抑郁 黑棘皮病 |
DOI:10.12025/j.issn.1008-6358.2017.20160212 |
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Abstract: |
Objective:To investigate the psychological depression of obese patients with acanthosis nigricans (AN), in order to provide evidence for clinical treatment. Methods:From March 2014 to August 2014, a total of 88 consecutive patients with obese were treated in our department, 56 age matched normal weight healthy volunteers were included as control group. They were divided into simple obesity group (OB, n=30) and obesity with acanthosis nigricans group (AN, n=58). The self administrated Beck Depression Inventory Ⅱ questionnaire was used in three groups, and general characteristics and clinical data were collected for analysis. Results:Compared with OB group, AN group had higher levels of FFA and UA (P<0.05). The severity of depression was significantly higher in AN group than OB group and the control group (P<0.05). The frequency of depression was recorded as 67.2% in the AN group, 43.4% in OB group, and 3.6% in control group (P<0.05). Conclusions:Obese patients with AN has severer metabolism disorder and severity of depression than simple obesity patients. Psychotherapy is necessary for AN patients when treat for obesity. |
Key words: obesity depression acanthosis nigricans |