纳米颗粒靶向策略在动脉粥样硬化诊断与治疗中的研究进展

Research progress of nanoparticle targeting strategy in diagnosis and treatment of atherosclerosis

摘要: 我国心血管疾病的患病率和致死率逐年上升。其中，动脉粥样硬化（AS）斑块不稳定和破裂是我国心血管疾病患者死亡的主要原因。随着纳米医学的进步，借助纳米颗粒（NPs）靶向诊治AS凸显出优势，近年来受到研究者的关注。

Abstract: The morbidity and mortality of cardiovascular diseases in China are increasing year by year. The unstable atherosclerosis (AS) plaque and plaque rupture are major factors leading to death in patients with cardiovascular diseases. With the progress of nanomedicine, targeted diagnosis and treatment of AS with nanoparticles (NPs) has shown its advantages and has attracted researchers’ attention in recent years.