Abstract:
Aortic stenosis (AS) is a structural change in aortic valve caused by congenital or acquired factors, and its incidence increases with age. Transcatheter aortic valve replacement (TAVR) is a safe and feasible minimally invasive treatment for severe AS. Since it was first approved by FDA in 2011 for severe AS which cannot be treated surgically, its indications have been extended to AS patients with low to moderate surgical risk. The placed prosthetic valves could compress the atrioventricular conduction system at the aortic root, leading to the development of postoperative cardiac conduction abnormalities, for which permanent pacemaker implantation (PPMI) is a treatment option. And post-TAVR PPMI is closely related to the prognosis of AS patients. Therefore, this article reviews predictors of conduction dysfunction and PPMI after TAVR.