| Efficacy analysis of high and low-power holmium laser enucleation in the treatment of benign prostatic hyperplasia with different volumes |
| Received:July 02, 2021 Revised:August 16, 2021 Click here to download the full text |
| Citation of this paper:JIANG Jie,GU Zhi-bo,CHEN Jian-gang,LU Ming.Efficacy analysis of high and low-power holmium laser enucleation in the treatment of benign prostatic hyperplasia with different volumes[J].Chinese Journal of Clinical Medicine,2021,28(5):846-852 |
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| Author Name | Affiliation | E-mail | | JIANG Jie | Department of Urology, the Second Affiliated Hospital of Nantong University, Nantong 226200, Jiangsu, China | | | GU Zhi-bo | Department of Urology, the Second Affiliated Hospital of Nantong University, Nantong 226200, Jiangsu, China | | | CHEN Jian-gang | Department of Urology, the Second Affiliated Hospital of Nantong University, Nantong 226200, Jiangsu, China | | | LU Ming | Department of Urology, the Second Affiliated Hospital of Nantong University, Nantong 226200, Jiangsu, China | storz888@aliyun.com |
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| Abstract:Objective: To explore the efficacy of high and low-power holmium laser enucleation in the treatment of benign prostatic hyperplasia (BPH) with different volumes, and to evaluate the feasibility of low-power holmium laser instead of high-power holmium laser for prostate enucleation in different volumes of BPH. Methods: A total of 163 patients with BPH who were admitted to the Department of Urology, The second Affiliated Hospital of Nantong University from January 2019 to December 2020 were selected. According to the size of the prostate, patients was divided into small and medium volume group (SMVG, 30n=90) and large volume group (LVG, V>80 mL, n=73), and the patients in each group were randomly divided into low power-holmium laser enucleation of the prostate (LP-HoLEP, 45 W) and high-power holmium laser enucleation of the prostate (HP-HoLEP, 80 W). The demographics, perioperative indicators, and postoperative complications of each group were collected and compared, and the postoperative follow-up was 6 months. Results: In SMVG, there was no statistically significant difference between LP-HoLEP and HP-HoLEP in the perioperative indicators and postoperative complications. In LVG, LP-HoLEP and HP-HoLEP had no statistically significant difference in comminuted time and postoperative complications, while in LP-HoLEP, the operation time (103.43 min vs 86.74 min, P<0.001) and enucleation time (83.53 min vs 65.30 min, P<0.001) was longer, the quality of enucleation of the prostate (65.30 mg vs 68.88 mg, P=0.02) was less, the enucleation efficiency (0.78 g/min vs 1.05 g/min, P<0.001) was lower, postoperative hospital stay (4.33 d vs 3.68 d, P<0.001) and catheter indwelling time (4.10 vs 3.20 d, P<0.001) were longer, and HB reduction value (8.78 g/L vs 9.85 g/L, P=0.02) was less. The IPSS and PVR of each group in the follow-up at 1 and 6 months after operation were lower than those before the operation, and Qmax was higher than before the operation, and the difference was statistically significant (P<0.05). Conclusions: LP-HoLEP and HP-HoLEP have the same curative effect in the treatment of small and medium volume BPH, and for large volume BPH, HP-HoLEP has a higher enucleation efficiency. |
| keywords:benign prostatic hyperplasia low power high power transurethral holmium laser enucleation of the prostate |
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