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Differences of clinical characteristics between non-obstructive and obstructive coronary myocardial infarction
Received:June 02, 2021  Revised:June 26, 2021  Click here to download the full text
Citation of this paper:WANG Ruo-chen,DAI Yü-xiang,GE Jun-bo.Differences of clinical characteristics between non-obstructive and obstructive coronary myocardial infarction[J].Chinese Journal of Clinical Medicine,2021,28(4):635-639
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Author NameAffiliationE-mail
WANG Ruo-chen Department of Cardiology, Fudan University, Zhongshan Hospital, Shanghai 200032, China  
DAI Yü-xiang Department of Cardiology, Fudan University, Zhongshan Hospital, Shanghai 200032, China
National Center For Radiation and Therapeutic Clinical Medicine, Shanghai 200032, China 
 
GE Jun-bo Department of Cardiology, Fudan University, Zhongshan Hospital, Shanghai 200032, China jbge@zs-hospital.sh.cn 
Abstract:Objective: To analyze the risk factors of morbidity, clinical manifestations, and short-term prognosis of non-obstructive coronary myocardial infarction (MINOCA).Methods: Totally, 838 patients with myocardial infarction who underwent coronary angiography in the Cardiac Intervention Center of Zhongshan Hospital, Fudan University from March 2020 to March 2021 were included. There were 77 MINOCA patients and 761 myocardial infarction patients complicated with obstructive coronary artery disease (MI-CAD). The high-risk factors, laboratory indexes, ECG, echocardiography, and the incidence of adverse events were compared between the two groups.Results: The proportions of males, hypertension, diabetes, and smoking in the MINOCA group were lower than those in the MI-CAD group (P<0.05). The levels of troponin T, N-terminal pro-brain natriuretic peptide (NT-proBNP), white blood cell count, and neutrophil count were lower in the MINOCA group than those in the MI-CAD group (P<0.001). The proportions of ST-segment elevation, abnormal wall systolic activity, and decreased ejection fraction in the MINOCA group were significantly lower than those in the MI-CAD group (P<0.001). There was no difference in the incidence of adverse events between the two groups.Conclusions: The incidence of MINOCA has no obvious gender tendency, the risk factors of MI-CAD are different from those of MI-CAD, and MINOCA patients have milder cardiac damage and better short-term prognosis.
keywords:non-obstructive coronary myocardial infarction  myocardial infarction with obstructive coronary artery disease  clinical characteristics  prognosis
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