| Application of quantitative CT in the pancreatic fat deposition in patients with type 2 diabetes |
| Received:April 30, 2021 Revised:June 22, 2021 Click here to download the full text |
| Citation of this paper:ZHU Hong,ZHANG Zong-jun,WU Fei-yun.Application of quantitative CT in the pancreatic fat deposition in patients with type 2 diabetes[J].Chinese Journal of Clinical Medicine,2021,28(4):598-602 |
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| Author Name | Affiliation | E-mail | | ZHU Hong | Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China
Department of Radiology, the Integrated Traditional Chinese and Western Medicine Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210028, Jiangsu, China | | | ZHANG Zong-jun | Department of Radiology, the Integrated Traditional Chinese and Western Medicine Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing 210028, Jiangsu, China | | | WU Fei-yun | Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China | wufeiyundd@163.com |
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| Abstract:Objective: To analyze the correlation and consistency of MRI IDEAL-IQ and quantitative CT (QCT) in the quantitation of pancreatic fat content in patients with type 2 diabetes.Methods: Sixty-seven volunteers with type 2 diabetes (33 men and 34 women, mean age years) underwent both MRI IDEAL-IQ and QCT examinations. The regions of interest (ROI) were placed at the head, body, and tail of the pancreas to obtain MRI pancreas fat fraction (MR-PFF) and CT-PFF. The correlation between MR-PFF and CT-PFF was analyzed, and the consistency of them was analyzed by Bland-Altman. The correlations between MR-PFF and liver fat content, abdominal circumference, and body mass index (BMI) were also analyzed.Results: In sixty-seven volunteers, the mean abdominal circumference was (83.34±10.1) cm, BMI was (24.02±2.96) kg/m2, and liver fat content was (5.28±2.76)%. The abdominal circumference and liver fat content were correlated with MR-PFF (P<0.05). MR-PFF and CT-PFF were (12.21±10.71)% and (19.9±10.61)%, respectively. CT-PFF showed a significant linear correlation with MR-PFF (r=0.842, P<0.001). MR-PFF=-4.169+0.818×CT-PFF. The Bland-Altman analysis results showed that the 95% CI of consistency was -4.15%-19.75% (P=0.044), and there were 3 values outside of the interval.Conclusions: The pancreatic fat contents measured by QCT and MRI have good correlation and consistency, and QCT can be used to measure pancreatic fat content. |
| keywords:fatty pancreas type 2 diabetes magnetic resonance quantitative CT pancreas fat fraction |
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