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Short term postoperative prognosis of patients with colorectal cancer liver metastasis after laparoscopic versus open repeat liver resection
Received:April 08, 2021  Revised:July 05, 2021  Click here to download the full text
Citation of this paper:ZHU Kai,SONG Dan-jun,ZHOU Jian,FAN Jia,WANG Xiao-ying.Short term postoperative prognosis of patients with colorectal cancer liver metastasis after laparoscopic versus open repeat liver resection[J].Chinese Journal of Clinical Medicine,2021,28(5):813-817
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Author NameAffiliationE-mail
ZHU Kai Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Liver Cancer Institute of Fudan University, Key Laboratory of Cancer Carcinogenesis and Invasion of Chinese Ministry of Education, Shanghai 200032, China  
SONG Dan-jun Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Liver Cancer Institute of Fudan University, Key Laboratory of Cancer Carcinogenesis and Invasion of Chinese Ministry of Education, Shanghai 200032, China  
ZHOU Jian Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Liver Cancer Institute of Fudan University, Key Laboratory of Cancer Carcinogenesis and Invasion of Chinese Ministry of Education, Shanghai 200032, China  
FAN Jia Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Liver Cancer Institute of Fudan University, Key Laboratory of Cancer Carcinogenesis and Invasion of Chinese Ministry of Education, Shanghai 200032, China  
WANG Xiao-ying Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Liver Cancer Institute of Fudan University, Key Laboratory of Cancer Carcinogenesis and Invasion of Chinese Ministry of Education, Shanghai 200032, China xiaoyingwang@fudan.edu.cn 
Abstract:Objective: To compare the safety and efficacy of repeat laparoscopic liver resection (LLR) and open liver resection (OLR) for patients with colorectal cancer liver metastasis (CRLM).Methods: A total of 289 patients with CRLM undergoing curative resection from January 2011 to December 2019 were enrolled and divided into LLR group (n=40) and OLR group (n=249). Propensity score matching (PSM) was performed as 1:2 in the LLR and OLR groups. The perioperative outcomes were compared between the two groups.Results: There was no perioperative death in the two groups. There was no statistically significant difference in blood transfusion rate, porta hepatis block time, and unplanned readmission rate within 30 days after surgery. After PSM, 40 patients in the LLR group and 80 patients in the OLR group were included. Compared with the patients in the OLR group, the intraoperative bleeding was less (50 mL vs 200 mL, P=0.001), the postoperative complication rate was lower (25.0% vs 47.5%, P=0.030), and the postoperative hospital stay was shorter (6 d vs 7 d; P=0.009) in the LLR group.Conclusions: CRLM patients who receive repeat LLR have better perioperative outcomes than those who receive repeat OLR.
keywords:colorectal cancer liver metastasis  recurrence  liver resection  laparoscopic  propensity score matching
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