| Effects of continuous blood purification on therapeutic efficiency in septic patients |
| Received:February 25, 2021 Revised:March 23, 2021 Click here to download the full text |
| Citation of this paper:XÜ Zhen-sheng,SHEN Yan-bo,ZHU Quan-jie,JIANG Dai-shan,YUAN Xiao-yü.Effects of continuous blood purification on therapeutic efficiency in septic patients[J].Chinese Journal of Clinical Medicine,2021,28(4):657-660 |
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| Author Name | Affiliation | E-mail | | XÜ Zhen-sheng | Department of Emergency Medicine, Branch of Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China | | | SHEN Yan-bo | Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China | | | ZHU Quan-jie | Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China | | | JIANG Dai-shan | Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China | | | YUAN Xiao-yü | Department of Emergency Medicine, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China | yxy11238@163.com |
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| Abstract:Objective: To analyze the effect of continuous blood purification (CBP) on the therapeutic efficiency in septic patients.Methods: A total of 122 patients diagnosed and treated in the Affiliated Hospital of Nantong University from October 2018 to December 2020 were randomly divided into the CBP group and conventional group, with 61 patients in each group. The patients in the conventional group received conventional treatment, and patients in the CBP group received CBP treatment on the basis of conventional treatment. The inflammatory factors (included tumor necrosis factor-α, interleukin-8, and interleukin-6), sepsis indicators, and hospitalization situation between the two groups before and after treatment were compared.Results: There were no statistically significant differences in the inflammatory factors and sepsis indicators between the two groups before treatment. The inflammatory factors and sepsis indicators were lower in the CBP group than those in the conventional group 1 week after treatment (P<0.01). Compared with the patients of in the conventional group, the length of stay in the intensive care unit and the total length of hospital stay of patients were shorter in the CBP group (P<0.001), and APACHE Ⅱ scores was also lower in the CBP group (P<0.01).Conclusions: For patients with sepsis, CBP can effectively suppress the indicators elevated due to sepsis while maintaining body fluid balance, and is hence of great significance in clinical applications. |
| keywords:intensive care unit sepsis continuous blood purification efficiency inflammatory response |
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