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Feasibility of coronary CT angiography in single cardiac cycle with wide-body detector in free-breathing state
Received:November 25, 2020  Revised:March 18, 2021  Click here to download the full text
Citation of this paper:ZHOU Lin-xi,LU Xiu-liang,ZHU Shuo,ZHOU Guo-feng,XÜ Shi-jie,ZOU Yi-xuan,YAN Cheng.Feasibility of coronary CT angiography in single cardiac cycle with wide-body detector in free-breathing state[J].Chinese Journal of Clinical Medicine,2021,28(4):622-628
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Author NameAffiliationE-mail
ZHOU Lin-xi Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
LU Xiu-liang Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
ZHU Shuo Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
ZHOU Guo-feng Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
XÜ Shi-jie Shanghai Lianying Medical Technology Co., Ltd., Shanghai 200032, China  
ZOU Yi-xuan Shanghai Lianying Medical Technology Co., Ltd., Shanghai 200032, China  
YAN Cheng Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China yancheng03yj@163.com 
Abstract:Objective: To investigate the feasibility of 320 slice CT angiography of coronary artery in patients with heart rate <75 times per minute in free-breathing state and to evaluate the image quality and radiation dose.Methods: Coronary artery CT imaging was performed in a single cardiac cycle using Lianying 320 slice CT by prospective electrocardiogram gating technique for 94 patients with suspected coronary heart disease and heart rate lower than 75 times per minute. The patients were divided into two groups according to their breathing patterns. There were 47 cases of breath-holding in group A and 47 cases of free-breathing in group B. Signal to noise ratio (SNR) of the aorta, contrast to noise ratios (CNR)of the aorta, left main trunk, proximal anterior descending artery, proximal circumflex artery, proximal and middle right coronary artery, were measured. Two radiologists evaluated 18 segments of the coronary artery of 94 patients by 5-point and double-blind methods, and score ≥ 3 meet the diagnostic requirements.Results: There was no significant difference in CNR, SNR, and CT values between the two groups. In group A and B, percentages of patients scored 5, 4, and 3 were 68.8% and 67.4%, 18.0% and 20.3%, and 10.2% and 10.4%, respectively. The radiation dose received by patients in group B was less that in the group A (P<0.01). Conclusions: There is no significant difference in image quality between free-breathing and standard breath-holding CCTA. Free-breathing CCTA is an acceptable solution for patients with heart rate lower than 75 times per minute.
keywords:coronary CT angiography  heart rate  free breathing  breath-hold  image quality
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